Regeneron Pharmaceuticals, Inc.

REGN · Health care (pharmaceutical preparations) · 10 years of annual accounts filed with the SEC · latest fiscal year ended 2025-12-31

Regeneron Pharmaceuticals, Inc. reported revenue of $14.3 billion in fiscal 2025, after growing 12.8% a year over the previous 9 years. Its operating margin narrowed from 27.4% in 2016 to 24.9%, and it earned 9.3% on its invested capital in the latest year. Of the $36.1 billion its operations generated over 10 years, 50.2% went to buybacks and 15.9% back into the business; the share count fell 6.6%. On the accounting screens, it passes 5 of 8 Piotroski tests and its Altman Z'' of 9.21 is in the safe zone; none of the six cross-checks between its statements fires.

Revenue, fiscal 2025 14.3B +12.8% a year over 9 years

Operating margin 24.9% gross margin —

Return on invested capital 9.3% 17.8% on average over 5 years

Free cash flow after stock pay 3.1B 21.5% of revenue

Net debt ÷ EBITDA Net cash 1.1B more cash than debt

Piotroski F-score 5/8 tests of improvement passed

Is it growing?

Revenue and the operating income it turns into. Growth that does not reach operating income is growth bought with margin.

RevenueOperating income

Compound growth a year
	3 yrs	5 yrs	9 yrs
Revenue	+5.6%	+11.0%	+12.8%
Operating income	-8.9%	+0.0%	+11.6%
Net income	+1.3%	+5.1%	+19.7%
Earnings per share	+2.8%	+6.3%	+20.6%
Free cash flow per share	-1.2%	+16.6%	+18.2%
Shares	-1.5%	-1.2%	-0.8%

Falling shares are buybacks: each remaining share owns more of the company.

Does it earn more than its capital costs?

Margins say how much of each sale is kept; return on invested capital says how much the business earns on the money it needs to operate. Growth only creates value when that return is above the cost of the capital.

    GrossOperatingNetFree cash flow
    
  

Return on invested capital

Return on invested capital Cost of capital today · 9.8%

Economic profit

(return on capital − cost of capital) × capital invested: the profit left after paying for the money used. Today's cost of capital is applied to every year, since a past one cannot be rebuilt honestly.

Return on equity: 14.4%
Return on assets: 11.1%
Asset turnover: 0.35×
Research & development: 40.8% of revenue
Overheads (SG&A): 18.8% of revenue

Is the profit cash, and where does the cash go?

Net income is an accounting opinion; free cash flow is what was left in the bank after investing. Stock-based pay does not leave the bank — shareholders pay it through dilution — so it is shown taken off as well.

Net incomeFree cash flowAfter stock-based pay

Where 10 years of operating cash went, 2016–2025

36.1B generated by the business. Each band is its share of that total.

Reinvested in the business 16% 5.7B
Acquisitions 1% 305.0M
Dividends 1% 370.3M
Share buybacks 50% 18.1B
Kept, or used to pay down debt 32% 11.6B

Over the same years it paid 6.6B in stock. The share count fell 6.6%. 11.6B of the buybacks went beyond offsetting that dilution.

Per share

    Earnings per shareFree cash flow per shareDividend per share
    
  

Shares outstanding

Diluted shares

How strong is the balance sheet?

Debt is not bad in itself; debt the business cannot service in a bad year is. Net debt is debt minus cash, and below zero the company holds more cash than it owes.

Net debt

Net debt ÷ EBITDA: -0.3×
Interest coverage: 82× operating income ÷ interest
Current ratio: 4.13 current assets ÷ current liabilities
Cash conversion cycle: — collects in 146d

Three classic screens of the accounts

Each asks a different question of the same statements — is it improving, does it look like a company heading for distress, do the accounts resemble ones that were manipulated. None is a verdict; each shows what moves it.

Piotroski F-score

Is the business improving? Nine yes-or-no tests, this year against last.

5of 8 tests passed

ProfitableReturn on assets above zero passed
Cash from operationsOperating cash flow above zero passed
Profitability improvedReturn on assets higher than a year before failed
Profit backed by cashOperating cash flow above net income (low accruals) passed
Less long-term debtLong-term debt as a share of assets fell passed
More liquidCurrent ratio higher than a year before failed
No new sharesShare count did not grow passed
Better gross marginGross margin higher than a year before — not reported no data
Sells more per assetAsset turnover higher than a year before failed

Where it misleads: it measures change, not level. An excellent business that stood still for a year scores low; a poor one recovering from a disaster scores high.

Altman Z''-score

Does the balance sheet look like those of companies that went bankrupt?

9.21safe zone

Working capital ÷ assets 0.34 × 6.56+2.21
Retained earnings ÷ assets 0.88 × 3.26+2.88
Operating income ÷ assets 0.09 × 6.72+0.59
Equity ÷ liabilities 3.36 × 1.05+3.53

Where it misleads: buybacks. A company that returns so much cash that its equity turns small or negative sinks the last two ratios without being anywhere near bankruptcy. Banks and insurers do not fit the model at all.

Beneish M-score

Do the accounts resemble those of companies that manipulated their earnings?

The accounts lack too many of the lines it needs.

Where the statements disagree

Cross-checks between the income statement, the balance sheet and the cash flow for the latest year, each with the benign reading and the worrying one.

None of the six cross-checks fires for the latest year: receivables and inventory move with revenue, profit turns into cash, investment keeps up with depreciation, the tax rate is ordinary and debt is moderate.

What is it worth, under which assumptions?

A company is worth the cash it will generate, brought back to today. This model projects revenue with growth that fades over the years, applies a free cash flow margin, and discounts the result at the cost of capital. Every assumption says where it came from, and all of them can be changed.

Revenue

Starting revenue

M $

revenue of fiscal 2025

Growth in year one

revenue grew +11.0% a year over the last 5 years; it fades to the terminal rate by the last year

Years until it settles

yrs

ten years for growth to fade to the terminal rate

Cash from each sale

Free cash flow margin today

free cash flow to the firm after stock-based pay ÷ revenue, last 3 fiscal years together

Margin in the last year

the margin in year ten; by default the business keeps today's

Count stock-based pay as a costIt is paid in shares instead of cash, and shareholders bear it through dilution. Most free cash flow figures leave it out.

The long run

Growth after that, forever

growth forever after year ten, below the risk-free rate: no company outgrows the economy forever

The discount rate

Risk-free rate

10-year US Treasury yield (FRED, DGS10), 2026-09-24

Beta

not measured on this public page, which uses only public filings: 1.0 assumes it moves like the market. Sign in to measure it from prices

Equity risk premium

the extra return demanded for holding shares; it cannot be measured, and 4–6% is the common range

Cost of debt, before tax

interest expense ÷ debt = 2.2%, kept between the risk-free rate and +8 points

Tax rate

effective rate in the last fiscal year, 13.9%, kept within 0–35%

The price

Share price

Type the price you see at your broker. It is used only for the reverse questions: what that price implies.

Back to the defaults

SEC from the filings Treasury the 10-year yield measured from prices assumption cannot be measured yours you changed it

Value per share, with these assumptions $380.46 discounted at 9.8% a year · 53% of it from after year 10

$291.5280% of 5,000 simulations$513.11

Cautious $245.93 7.0% growth · 12.1% margin · 10.8% discount · 2.0% forever

Your assumptions $380.46 11.0% growth · 14.2% margin · 9.8% discount · 2.5% forever

Generous $621.18 15.0% growth · 16.4% margin · 8.8% discount · 3.0% forever

Type a share price on the left to ask the reverse questions: what growth, what margin or what discount rate that price implies.

What the value implies, in the usual multiples

	At this model's value
Price ÷ earnings	9.2×
Enterprise value ÷ EBITDA	9.7×
Enterprise value ÷ revenue	2.8×
Free cash flow yield	7.5%

From cash flows to a value per share

10 years of cash flow, today18.8B

Everything after, today21.4B

The whole business40.2B

Plus net cash1.1B

What belongs to shareholders41.3B

Divided among 108.6M shares: $380.46 each.

The projection next to its history

Reported free cash flow after stock pay, then the model's. A projection that looks nothing like the past needs a reason.

ReportedProjected

Year by year

	2026	2027	2028	2029	2030	2031	2032	2033	2034	2035
Revenue	15.9B	17.5B	19.1B	20.7B	22.2B	23.6B	24.8B	25.9B	26.8B	27.5B
Growth	11.0%	10.1%	9.1%	8.2%	7.2%	6.3%	5.3%	4.4%	3.4%	2.5%
Cash margin	14.2%	14.2%	14.2%	14.2%	14.2%	14.2%	14.2%	14.2%	14.2%	14.2%
Free cash flow	2.3B	2.5B	2.7B	2.9B	3.2B	3.4B	3.5B	3.7B	3.8B	3.9B
Worth today	2.1B	2.1B	2.1B	2.0B	2.0B	1.9B	1.8B	1.7B	1.6B	1.5B

If the least-known inputs move

Value per share as two inputs change at a time. Neighbouring cells that differ a lot are the conclusion: the value depends on numbers nobody knows to a point.

The discount rate and growth forever

discount ↓ · forever →	1.5%	2.0%	2.5%	3.0%	3.5%
8.8%	393	416	442	472	509
9.3%	367	387	409	435	465
9.8%	344	361	380	402	428
10.3%	324	339	356	374	396
10.8%	306	319	334	350	368

Year-one growth and the final margin

margin ↓ · growth →	7.0%	9.0%	11.0%	13.0%	15.0%
11.4%	277	299	323	348	375
12.8%	301	326	352	380	409
14.2%	326	352	380	411	444
15.7%	350	378	409	442	478
17.1%	374	405	438	474	512

All the inputs moving at once

5,000 valuations, each with growth, final margin, discount rate and growth forever drawn at random around the values on the left (spreads of 3.0%, 2.1%, 1.0% and 0.5%). Not a probability — the spreads are assumptions too — but an honest picture of how wide the answer is.

10th percentile$291.52

Median$381.05

90th percentile$513.11

Half of the simulations land between $329.31 and $441.86; one in ten below $291.52, one in ten above $513.11.

Does the long run make sense?

6.9×The terminal value prices the business in year 10 at 6.9 times that year's EBITDA.
7%To grow 2.5% forever while reinvesting 34% of its after-tax operating profit, the business must earn 7% on the new capital — it has earned 18% on average over the last five years.
53%of the value comes from after year 10. The more of it, the more the answer depends on the part nobody can see.

The discount rate, taken apart

What shareholders demand (CAPM): 5.18% risk-free + 1.00 beta × 5.0% premium = 10.18%.
What lenders charge, after the tax saving on interest: 5.18% × (1 − 13.9%) = 4.46%.
Weighted by how much of each the company uses (book value (no price given)): 9.84%, the rate every future cash flow is discounted at.

What it has filed lately

The last twelve months at the SEC, most important first: annual and quarterly reports, events, large holders and insiders.

Published the results of a shareholder vote

Estimatein 33d

Results for the period ending 2026-09-29

Companies like this one

Same SEC industry (pharmaceutical preparations) first, then the rest of health care.

LLY ELI Lilly & Co JNJ Johnson & Johnson ABBV AbbVie Inc.MRK Merck & Co., Inc.ABT Abbott Laboratories PFE Pfizer Inc VRTX Vertex Pharmaceuticals Inc / MA BMY Bristol Myers Squibb Co

Every figure, year by year

10 fiscal years · 30 measures

	2016	2017	2018	2019	2020	2021	2022	2023	2024	2025
Size
Revenue	4.9B	5.9B	5.1B	6.6B	8.5B	16.1B	12.2B	13.1B	14.2B	14.3B
Revenue growth	—	+20.8%	-12.4%	+27.4%	+29.6%	+89.1%	-24.3%	+7.8%	+8.3%	+1.0%
Operating income	1.3B	2.1B	2.5B	2.2B	3.6B	8.9B	4.7B	4.0B	4.0B	3.6B
Net income	895.5M	1.2B	2.4B	2.1B	3.5B	8.1B	4.3B	4.0B	4.4B	4.5B
Margins
Gross margin	96.0%	96.6%	95.4%	93.9%	—	—	—	—	—	—
Operating margin	27.4%	35.4%	49.3%	33.7%	42.1%	55.7%	38.9%	30.9%	28.1%	24.9%
Net margin	18.4%	20.4%	47.5%	32.3%	41.3%	50.2%	35.6%	30.1%	31.1%	31.4%
Free cash flow margin	20.0%	17.6%	35.2%	30.5%	23.6%	40.6%	36.3%	29.5%	25.8%	28.4%
R&D ÷ revenue	42.2%	35.3%	28.5%	37.4%	31.2%	17.8%	29.5%	33.8%	36.1%	40.8%
SG&A ÷ revenue	24.2%	22.5%	21.9%	20.5%	15.8%	11.4%	17.4%	20.1%	20.8%	18.8%
Cash
Free cash flow	974.0M	1.0B	1.8B	2.0B	2.0B	6.5B	4.4B	3.9B	3.7B	4.1B
Stock-based pay	559.9M	507.3M	427.4M	464.3M	432.0M	601.7M	725.0M	885.0M	982.8M	993.7M
Free cash flow after stock pay	414.1M	527.2M	1.4B	1.5B	1.6B	5.9B	3.7B	3.0B	2.7B	3.1B
Free cash flow to the firm	488.9M	728.3M	1.6B	1.3B	460.5M	5.6B	4.3B	3.0B	2.5B	3.2B
Free cash flow ÷ net income	1.1×	0.9×	0.7×	0.9×	0.6×	0.8×	1.0×	1.0×	0.8×	0.9×
Capex ÷ revenue	10.5%	4.6%	7.4%	6.6%	7.2%	3.4%	4.8%	5.5%	5.3%	6.3%
Returns
Return on invested capital	—	—	—	17.4%	25.4%	37.3%	17.2%	13.6%	11.8%	9.3%
Return on equity	20.1%	19.5%	27.9%	19.1%	31.9%	43.0%	19.1%	15.2%	15.0%	14.4%
Return on assets	12.8%	13.7%	20.8%	14.3%	20.5%	31.7%	14.9%	12.0%	11.7%	11.1%
Asset turnover	0.7×	0.7×	0.4×	0.4×	0.5×	0.6×	0.4×	0.4×	0.4×	0.4×
Economic profit	—	—	—	833.7M	2.0B	5.7B	1.8B	1.1B	600.9M	-189.1M
Per share
Earnings per share	$7.70	$10.34	$21.29	$18.46	$30.52	$71.97	$38.22	$34.77	$38.34	$41.48
Free cash flow per share	$8.37	$8.93	$15.78	$17.46	$17.41	$58.19	$38.99	$34.08	$31.84	$37.57
Dividend per share	—	—	—	—	—	—	—	$0.00	$0.00	$3.41
Payout ratio	—	—	—	—	—	—	—	0.0%	0.0%	8.2%
Book value per share	$38.26	$53.01	$76.28	$96.77	$95.79	$167.28	$199.68	$228.44	$255.03	$287.82
Diluted shares	116.3M	115.9M	114.8M	114.6M	115.1M	112.2M	113.5M	113.7M	115.1M	108.6M
Balance sheet
Net debt	—	—	—	-1.6B	-215.2M	-905.6M	-1.1B	-747.1M	-503.8M	-1.1B
Net debt ÷ EBITDA	—	—	—	-0.7×	-0.1×	-0.1×	-0.2×	-0.2×	-0.1×	-0.3×
Interest coverage	184.8×	82.9×	89.9×	73.2×	62.9×	156.1×	79.8×	55.4×	72.3×	81.7×
Current ratio	2.6×	3.8×	4.5×	3.7×	3.6×	3.6×	5.1×	5.7×	4.7×	4.1×
Cash conversion cycle (days)	—	1,083	1,556	1,021	—	—	—	—	—	—
Scores
Piotroski F-score	—	7	5	5	4	6	5	5	4	5
Altman Z''	5.77	7.55	8.80	8.24	8.06	10.35	10.19	10.53	9.67	9.21
Beneish M	—	-2.34	-2.21	-2.40	—	—	—	—	—	—

Accounts from the company's own SEC filings; lines some companies do not report are shown as a dash rather than estimated. The risk-free rate is the 10-year US Treasury yield. A DCF is a way of making assumptions explicit, not a forecast: it states what the company would be worth if the assumptions held. The scores are screens that point where to look, not verdicts. Nothing here is a recommendation to buy or sell.